[A case of asymptomatic primary biliary cirrhosis associated with multiple myeloma and atrophic thyroiditis].
نویسندگان
چکیده
概要 原発 性胆 汁性肝硬 変(P3C)にmonoclonal gammopathや 多発性 骨髄 腫 の合併 は まれ で あ るが,無 症 候性PBCに 多発性骨髄 腫 を合併 し,そ の後原 発姓 甲状腺機 能低 下症 を発症 した 70才 女性 を経 験 した.三 老の ほ ぼ平 行 した増 悪 と治 療 に よ る改 善 が み られ,ス テ ロイ ド薬 と cyclophosphamideに よる化学療 法で骨髄像,血 中 γ・グ ロブ リン値 の改善 に伴 って抗 ミ トコ ン ドリア抗体 価,血 中IgM,ア ル カ リフォス フ ァターゼ値,抗 マ イク ロゾーム抗体 価 は著 明 に低 下,同 時 に血 中TSH binding inhibitor immunoglobulinの 改善 を伴 って甲状 腺機能 も正 常化 した.本 例 にお ける これ ら三 つの病 態 の密接 な関連が 示唆 され た. 〔日内会 誌 76:528~532, 1987〕
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ورودعنوان ژورنال:
- Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine
دوره 76 4 شماره
صفحات -
تاریخ انتشار 1987